Proliferative Indices, Ki-67 Immunostaining and Nucleolar Organizer Region Associated Protein and their Association with Various Grades of Breast Carcinomas
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چکیده
Material and Methods: The present study was conducted on 40 specimens of breast carcinoma out of which 12 cases were of Grade II and 28 cases were of Grade III. Percentage positivity and scoring of Ki-67 and mean AgNOR count was done with relation to grades. Observations: Ki-67 positivity was seen in 12 cases with the percentage positivity of 2.33±5.516 in grade II and 9.67±7.671 in grade III tumours . Similarly Mean AgNOR count in grade II was 3.39±0.79 and 4.28±1.07 in grade III cases. Mean Ki-67 positivity was 7.2% in cases showing metastatic deposits and it was 6.3% in cases with reactive pathology in lymph nodes.
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